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Virtual Entity Yields Real-Time Results

Genomic technologies have revolutionized cancer research, but not without analytical challenges. No single researcher can manage the vast datasets generated by next-generation sequencing and other modern genomic tools. Harnessing those tools in the pursuit of translational advances increasingly compels team science and multidisciplinary collaboration. Toward that end, NCI’s Center of Excellence in Integrative Cancer Biology and Genomics (CEICBG) was created in 2008 to unite experts in cancer biology with colleagues in bioinformatics. Read more about how virtual entities can yield real-time results »

Training the Next Generation of Cancer Researchers

Staffed by nearly 250 principal investigators (PIs) and linked to the world’s largest, publicly funded research hospital, CCR offers a wealth of opportunities for graduate and postgraduate training. At CCR, predoctoral students along with postdoctoral and clinical fellows work at the intersection of basic science and clinical medicine. And with ready access to patients, clinical trials, tumor samples, and advanced technology, CCR’s aspiring investigators pursue translational research in a collaborative setting that puts a high priority on professional development. Read more about training the next generation of cancer researchers »

It Starts with a Choice: Cancer Cells and Their Decisions to Replicate

A Senior Investigator in CCR’s Laboratory of Molecular Pharmacology (LMP), Mirit Aladjem, Ph.D., has a long-held fascination with the choices cells make when DNA replication goes awry. She realized that the use of alternative signaling pathways lies at the heart of cancer’s survival mechanisms—cells that choose to replicate unstable DNA and then divide can seed tumors, while those that choose to self-destruct by apoptosis can impede tumor growth. Read more about cancer cells and their decisions to replicate »


Photo of Robert Wiltrout, Ph.D.

Producing Scientific Synergism

In this issue, we showcase how CCR’s basic researchers generate discoveries with downstream relevance for better patient care.…


Photo of Peter C. Adamson, M.D.

Tackling Drug Resistance Mechanisms in the Stroma

Dr. Ostrowski is currently Professor and Chair of the Department of Molecular and Cellular Biochemistry at The Ohio State University Medical Center (OSUMC), in Columbus.


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