Th17 Immune Cells in vivo: Friend or Foe?
Upon encountering an antigen, T cells bearing CD4+ (a helper marker) proliferate and become polarized. Learn more about Th17 immune cells...
Posted: 12/2011
Mapping Cancer Cells’
Starting Lines
Many of the defective regulatory pathways that lead to aberrant proliferation in cancer converge on DNA replication. Learn more about replication start sites...
Posted: 11/2011
Targeted Infrared Photoimmunotherapy
for Cancer
A longstanding goal of cancer therapy is the extensive destruction of cancer cells with minimal collateral damage to normal cells. Learn more about targeted photoimmunotherapy...
Posted: 10/2011
From SHAPE Signatures to
3-D Structures
RNAs undergo extensive folding to form sophisticated based-paired secondary structures that are, in part, indicators of more complex three-dimensional structures. Learn more about SHAPE Signatures...
Posted:10/2011
For Nicotine, Dose Matters
Nicotine replacement therapy (NRT) is frequently part of a person’s regimen for smoking cessation. Learn more about nicotine replacement therapy...
Posted: 10/2011
New Technique Identifies First Events in Translocations
A novel technique that enables scientists to measure and document tumor-inducing changes in genomic DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas. Learn more about this novel technique...
Posted: 10/2011
Recombination Origin of Retrovirus XMRV
Xenotropic murine leukemia virus–related virus (XMRV) was first reported in samples from a human prostate tumor in 2006. Learn more about the retrovirus XMRV...
Posted: 10/2011
Stem-Like Memory T Cells
Are Discovered
T cells are the white blood cells that are the body’s first line of attack against foreign invaders. Learn more about how stem-like memory T cells are discovered...
Posted: 9/2011
BRCA1 Variants Co-Conspire
With MicroRNA-155
Recently discovered microRNAs (miRNAs) have an important biological role by switching “on” and “off” at different times during cell growth, death, development and differentiation. Learn more about the role of microRNAs...
Posted: 9/2011
Interleukin-8 and Its Role
During EMT
An understanding of the signaling events that induce tumor EMT could lead to novel ways to prevent metastasis. Learn more about Interleukin-8 and its role during EMT...
Posted: 9/2011
Somatic Cells Become Cancer’s “Starter Dough”
Somatic cells possess enough plasticity to reprogram and acquire CSC-like propertiesLearn more about somatic cells. . .
Posted:08/2011
AP1 Keeps Chromatin
Poised for Action
The human genome harbors gene-encoding DNA, the blueprint for building proteins that regulate cellular function. Read more about AP1...
Posted: 07/2011
Top1 May Do More Than
Relax DNA
Topoisomerase 1 (Top1) is an enzyme with a well known role in relaxing DNA supercoils by making reversible nicks in DNA. Learn more about Topoisomerase 1...
Posted: 06/2011
When No Response Is a
Good Thing
Custom-designed therapies that target cell-surface antigens or receptors represent a promising immunological approach in cancer therapy. Learn more about custom-designed therapies...
Posted: 6/2011
