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All Tumor Cells Are Not Created Equal

Rare cell divisions are asymmetric, generating daughter cells that may differ in size, developmental potential, or even DNA content. Read more about asymmetric cell division. . .

Is It Just a Mole, or Is It More?

Fast and reliable tests that accurately detect and characterize cancer are a major goal in cancer research. Read more about cancer detecting tests. . .

FasL Mediates T-Cell Eradication of Tumor Cells Presenting Low Levels of Antigens

One approach to cancer immunotherapy, as opposed to therapeutic vaccination, is the transfusion of large numbers of tumor-specific killer T cells (cytotoxic T cells or CTLs) into patients. Read more about killer T cells. . .

Cullin 5: A Destabilizing Force for Some Oncogenes

Cancer can result when cellular processes such as proliferation and cell death go haywire. Read more about cullin 5. . .

Riding the Waves: How Our Cells Send Signals

The ability of cells to perceive and respond to their environment is critical in order to maintain basic cellular functions such as development, tissue repair, and response to stress. Read more about how cells send signals. . .

Molecular Clues to Physiological and Premature Ageing Revealed

There are many theories about the molecular basis of ageing. Read more about premature ageing. . .

The Two Faces of p53 in Embryonic Stem Cells

Mutations in the genome of a cell can have dire effects. Read more about the two faces of p53. . .

Making Sense Out of Antisense RNA Regulation

Inappropriate gene expression can lead to the development of diseases such as cancer. Read more about vorinostat. . .

Ganging Up on Brain Metastases

When primary tumors metastasize to the brain, the prognosis for patients is poor. Read more about RNA regulation. . .

The Ups and Downs of Glucocorticoid Signaling

Glucocorticoids are steroids that react to stress by regulating inflammation and controlling metabolism. Read more about glucocorticoids. . .

Uncovering the Path
That Leads to Diabetes

The origins of diabetes have been the subject of intense scientific research, but the genetic factors that cause certain people to develop the disease have remained elusive. Read more about diabetes. . .

CD8+ T Cells Need a Little Help(er) for Sustained Antitumor Response

The immune system comprises a powerful army of specialized cells and molecules that protect the body against invading foreign agents.Read more about the immune system. . .

BMI1 and H-RAS Cooperate to Drive Breast Cancer Metastasis

There have been significant improvements in the diagnosis of breast cancer at early stages of the disease. Read more about the diagnosis of breast cancer . . .

CLIC4 Moves Into Nucleus to Stabilize Anti-Growth Signal

In cancer, the delicate balance of signaling pathways that control cell growth and function is disrupted. One signaling pathway commonly altered in cancer is the TGF-beta pathway. Read more about CLIC4 . . .

Note: All questions should be directed to Donna Kerrigan


CCR In The Journals Archive