Effect of HMGN on Nucleosome Accessibility and Modification

Using cells from knock-out mice and in vitro reconstitution system, we find that HMGNs affect the levels of posttranslational modifications in histone tails.

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HMGN1 affects the levels of modification in the tail of H3	Distinct domains in HMGNs affect specific histone modifications

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Last revised on July 18, 2006 by Linda G. Byrd, Ph.D.

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Effect of HMGN on Nucleosome Accessibility and Modification	Michael Bustin, Ph.D., Chief, Protein Section, LM, CCR, NCI, NIH

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