From:                                                                            Ji, Xinhua (NIH/NCI) [E]

Sent: Saturday, November 4, 2023 9:09 AM

To:                                                                                List NIHXRAY-L

Subject: Newsletter 501 (November 6, 2023) NIH X-ray Diffraction SIG

 

 

 

OCTOBER 2023 PUBLICATIONS BY MEMBERS OF THE GROUP

 

1: Chen X, Walters KJ.

^{1H, 15N, 13C resonance assignments for proteasome shuttle factor hHR23a}.

Biomol NMR Assign. 2023 Oct 9.

doi: 10.1007/s12104-023-10157-z. Epub ahead of print. PMID: 37812322.

 

2: Ding J, Deme JC, Stagno JR, Yu P, Lea SM, Wang YX.

Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.

Nucleic Acids Res. 2023 Oct 13;51(18):9952-9960.

doi: 10.1093/nar/gkad651. PMID: 37534568; PMCID: PMC10570017.

 

3: Du L, Wilson BAP, Li N, Shah R, Dalilian M, Wang D, Smith EA, Wamiru A, Goncharova EI, Zhang P, O'Keefe BR.

Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.

J Nat Prod. 2023 Oct 27;86(10):2283-2293.

doi: 10.1021/acs.jnatprod.3c00394. Epub 2023 Oct 16. PMID: 37843072; PMCID: PMC10616853.

 

4: Collins JC, Magaziner SJ, English M, Hassan B, Chen X, Balanda N, Anderson M, Lam A, Fernandez-Pol S, Kwong B, Greenberg PL, Terrier B, Likhite ME, Kosmider O, Wang Y, Samara NL, Walters KJ, Beck DB, Werner A.

Shared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases.

bioRxiv [Preprint]. 2023 Oct 10:2023.10.10.561769.

doi: 10.1101/2023.10.10.561769. PMID: 37873213; PMCID: PMC10592724.

 

5: Wojtaszek JL, Hoff KE, Longley MJ, Kaur P, Andres SN, Wang H, Williams RS, Copeland WC.

Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.

Nucleic Acids Res. 2023 Oct 13;51(18):9716-9732.

doi: 10.1093/nar/gkad679. PMID: 37592734; PMCID: PMC10570022.

 

6: Pan Y, Zhan J, Jiang Y, Xia D, Scheuring S.

A concerted ATPase cycle of the protein transporter AAA-ATPase Bcs1.

Nat Commun. 2023 Oct 11;14(1):6369.

doi: 10.1038/s41467-023-41806-5. PMID: 37821516; PMCID: PMC10567702.

 

7: Yang Y, Boardman E, Deme J, Alcock F, Lea SM, Palmer T.

Three small partner proteins facilitate the type VII-dependent secretion of an antibacterial nuclease.

mBio. 2023 Oct 10:e0210023.

doi: 10.1128/mbio.02100-23. Epub ahead of print. PMID: 37815362.

 

8: Erickson R, Huang C, Allen C, Ireland J, Roth G, Zou Z, Lu J, Lafont BAP, Garza NL, Brumbaugh B, Zhao M, Suzuki M, Olano L, Brzostowski J, Fischer ER, Twigg HL 3rd, Johnson RF, Sun PD.

SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition.

Nat Commun. 2023 Oct 11;14(1):6380.

doi: 10.1038/s41467-023-42140-6. PMID: 37821447; PMCID: PMC10567911.

 

9: Appel CD, Bermek O, Dandey VP, Wood M, Viverette E, Williams JG, Bouvette J, Riccio AA, Krahn JM, Borgnia MJ, Williams RS.

Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2.

Mol Cell. 2023 Oct 19;83(20):3692-3706.e5.

doi: 10.1016/j.molcel.2023.09.024. Epub 2023 Oct 12. PMID: 37832548.

 

10: Koscielniak J, Li J, Sail D, Swenson R, Anklin C, Rozovsky S, Byrd RA.

Exploring Sulfur Sites in Proteins via Triple-Resonance ¹H-Detected ⁷⁷Se NMR.

J Am Chem Soc. 2023 Oct 31.

doi: 10.1021/jacs.3c07225. Epub ahead of print. PMID: 37906952.

 

 

METHODS – Cryo-EM in Structure-Based Drug Design

 

I. Victorial et al. “High-resolution cryo-electron microscopy of the human CDK-activating kinase for structure-based drug design”

bioRxiv preprint doi: https://doi.org/10.1101/2023.04.07.536029; this version posted April 12, 2023.

 

 

METHODS - Macromolecular Crystallography

 

W.A. Hendrickson, “Facing the phase problem” PMID: 37668214

J.L. Smith, “Commentary on ‘Facing the phase problem’ by Wayne Hendrickson” PMID: 37615300.

 

Xinhua Ji, Ph.D.

Senior Investigator

National Cancer Institute, NIH

Phone: (301) 846-5035